Cannabigerol, or CBG, is a non-psychoactive cannabinoid typically most abundant in low-THC and high-CBD hemp plants. In much a similar way to CBD, CBG stimulates the cannabinoid receptors in the brain and alleviates any "high" created by THC.
Scientists have known about CBG for over 70 years. CBG was first isolated by Raphael Mechoulam and his team at the Hebrew University in Israel in 1964. However, it took Japanese scientists 30 years to reveal that CBGA was the precursor of CBG ("A" stands for acid). They discovered that it was produced in the resin glands of mature female hemp plants. Unlike THC, consuming CBG won’t get you high. Infact, it is believe that CBG counteracts the psychotropic effects of THC in very much the same way CBD does!
What’s interesting about the discovery made by Japanese scientists, is that the acidic form of CBG, CBGA, plays a huge role in the synthesis of other phytocannabinoids (namely THCA and CBDA) as well as determining the metabolic lifespan of the hemp plant, which is where its nickname "mother cannabinoid" or "grandfather cannabinoid" comes from.
What are the differences between CBG and CBD?
Like CBD, CBG is non-psychoactive, but it is able to alter a person’s state of mind in a way that could relieve anxiety and depression.
CBG has been found to be more potent than CBD, and its possible medical benefits include pain relief, reducing bacterial growth, calming inflammation and helps other sicknesses such as nausea. It also has shown to slow the proliferation of cancer cells. Research has shown it also significantly reduces intraocular eye pressure caused by glaucoma. Strains high in CBG will be beneficial treating conditions such as inflammatory bowel disease and It can also be used to promote energy. CBG has displayed strong anti-anxiety effects, and has a muscle-relaxing reaction, both of which are connected to the same nervous system. This is due to CBG binding to certain endocannabinoid receptors in the brain that ease anxiety and pain.
So, the primary difference is that CBD and CBG are chemically distinct due to their particular physicochemical properties and interactions with the endocannabinoid system. Serving separate purposes, each with the possibility to help treat various maladies and symptoms.
In 2015, CBG was shown to protect neurons in mice with Huntington’s disease; characterised by nerve cell degeneration in the brain. CBG was also shown to protect the nervous system from potential damage. Your nervous system needs to accurately control your blood pressure, heart rate, body temperature, etc. Research also shows evidence that CBG is an effective antibacterial agent, particularly against MRSA microbial strains which are resistant to other classes of drugs. Topical cannabis has been effective in skin infections and doesn’t come with the harmful side effects that occur to the gut prescription antibiotics bring.
One isn't better than the other when it comes to CBD and CBG, it just depends on personal preference and needs! Both carry amazing benefits!